Founded in 1933 as part of President Franklin Roosevelt’s New Deal programs, the Tennessee Valley Authority (TVA) was created to infuse economic development by tackling environmental, health, and technological issues in the region. Anopheles quadrimaculatusmosquito control was a key part part of TVA planning given the rise of malaria incidence during the Great Depression. Not only did vector control in the Tennessee Valley pose challenges; the TVA called for the construction of dams to control flooding and generate hydroelectric power – construction that would create 10,000 miles of new shoreline. The resulting plan introduced a revolutionary combination of source reduction, habitat modification and manipulation, chemical control, and application technology that has since informed decades of Larval Source Management programs around the world.